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Preheat the oven to 350 F. Line muffin pan with red cupcake liners.
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In a medium bowl, whisk the flour, cocoa powder, baking soda, and salt. Set aside.
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In a large bowl, beat the butter and sugar until light and fluffy.
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Add the egg and vanilla and beat until combined.
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Stir the vinegar and red food coloring into the buttermilk.
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Add the flour mixture to the butter mixture, mixing on low speed. Add in the buttermilk and beat until smooth.
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Pour the batter into prepared muffin, filling each cup halfway.
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Bake the cupcakes for 15-18 minutes or until a toothpick inserted in the center comes out clean. Let the cupcakes cool for 5 minutes in the pan before transferring them to a wire rack to cool completely.